The plot features Ronald and the gang out on a journey to Grimace Island where Grimace's species is discovered. Grimace previously received a letter which was actually written by the pirate captain One-Eyed Sally and her first mate Blather. The two pirates follow them to capture the treasure on the island.

While helping Franklin clean up his father's lab, Ronald and his pals stumble across a time machine. Hamburglar dreams up a crazy scheme to use the time machine to get out of cleaning and they end up getting lost in time. Their time travel adventures take them to prehistoric times where the time machine is nearly digested by a Tyrannosaurus and they meet their cavemen ancestors, the medieval times where they impress the crabby King Murray with a musical number to save captured Birdie, the wild wild west where they discover Hamburglar's ancestor Henry H. Burglar II, whom the residents mistake Hamburglar for, and the disco era of the '70s where they briefly encounter Mayor McCheese.

In the 1960s a young woman works at NASA as an animal trainer responsible for the chimpanzee who will go into space.

Ronald and his friends going on a camping trip in the Far-Flung Forest where Ronald discovers an old house which he assumes is haunted by a ghost called the Far-Flung Phantom. The campers are forced to stay in the old house due to the stormy weather where a holographic head named Franklin leads them through a challenging game which will eventually help them to escape.

凯西和乔治是一对欢喜姐弟，平时乔治和他的死党弗瑞德是以作弄姐姐凯西为乐的顽皮鬼，而凯西每日都在网络上梦想到巴黎和浪漫的帅哥约会，某日两人的父母要出外旅行，保姆玛蒂达负责照顾他们俩。乔治在父母出门后将家中搞得翻天覆地，而玛蒂达不处罚他，凯西看得非常生气，而设计乔治进入玛蒂达的房间中搞乱希望玛蒂达生气而处罚乔治，但奇妙的事情发生了，乔治在玛蒂达的房间中无意发现了一个宝箱，而箱中装了神奇的魔法将乔治变成了——猪，原来玛蒂达来自一个墨西哥巫师的家庭，玛蒂达和凯西知道后非常的紧张，玛蒂达、凯西、弗瑞德和变成小猪的乔治共同踏上前往墨西哥的路上寻找将乔治变回人的方法……