白宫官邸出了人命，所有国宴现场的职员和宾客都有嫌疑，一名优秀怪咖侦探必须解决这桩谋杀案。

Donner and his roomates are out of money and about to get evicted from their home. So as a diversion from their situation, he invites them to his father's cabin in the Canadian wilderness. They all go along, but soon learn that there's no cabin - he's really trying to find Sasquatch.

Earl（由出演过“成名在望”和“Chasing Amy”的Jason Lee扮演）在自己的人生道路上多次选错了方向，现在又有一件可能改变自己命运的事情发生：他中了一小笔彩票奖金。在主现日后，他决心要让这种好运去改变自己的生活，将自己从错误的方向上纠正过来。
但是，在Earl的新生活开始之前，一些不幸的事情又不期而至：刚得知中奖后，他就被汽车撞了；更不幸的是，中奖的彩票不翼而飞。在医院的病床上，Earl无意看到了一个电视节目“与Carson Daly的最后一次通话”，Carson在节目中说他的成功是因为做好事而得到老天的回报，Earl顿悟，原来自己的霉运都是因果报应的结果。于是，Earl决定开始去弥补自己以往犯下的所有过失，他选择的第一个对象是小学时自己的作弄对象：书呆子Kenny
Earl的一群傻瓜朋友也加入了他的行动：他的倒霉兄弟Randy（出演过“冷山”的Ethan Suplee），非常性感的Catalina（出演过“The Bold and the Beautifu”的Nadine Velazquez）。Earl经常光顾的酒馆老板Even Darnell （出演过"Torque"的Eddie Steeples）给与他支持。但Earl的前妻Joy（出演过"Not Another Teen Movie"的Jamie Pressly）却无动于衷，除非她能得到什么好处。
不管Early的举动看上去有多么愚蠢，他却得到了意想不到的回报，这也是此剧创作者想告诉观众的一句老话：好人有好报！
Earl Hickey's life has been full of poor choices and mistakes, but after winning a small lottery jackpot he has an epiphany and vows to change his ways. Upon discovering that he is the holder of a winning ticket, Earl is hit by a car and the ticket blows out of his limp hand as he lies unconscious in the street. While recovering in the hospital and watching television, Earl has a karmic epiphany, thanks to Carson Daly, who attributes his success to doing good for others. A light bulb goes off in Earl's dim head and he sets out to right every wrong he has done starting with a grade school geek.

Ethan Tell is a small time crook who makes a big-time score when he steals 1 million dollars. Ironically, his life radically changes for the worst when he discovers that stealing the money was the easy part and he now must keep his partner, his wife, his parole officer, and two corrupt detectives from stealing it from him.