After a nuclear attack, an unlikely group of survivors, including a geologist, a crook and his moll, and a prospector, find temporary shelter in the remote-valley home of a survivalist and his beautiful daughter, but soon have to deal with the spread of radioactivity - and its effects on animal life, including humans.

An artist working in a remote army post is juggling the storekeeper's daughter, his fiancée newly arrived from the east, and the Indian Chief's daughter. But when a vengeful settler manages to get the army and the braves at each other's throats his troubles really begin.

Francis the talking mule gets his owner in and out of trouble while he is taking basic training at West Point.