When a man returns from a trip unwittingly harboring a new breed of arachnid, the people in an apartment block are quarantined and left to fend for themselves against a plague of venomous spiders.

Four of the West's most infamous outlaws carry out a daring bank heist in the gold-rush town, Bath Water. As the posse takes chase, things take a turn for the worse, as the bandits realize they've been double-crossed - but by who?