Fact-based drama about the life of Marie Balter, who spent most of her young life in mental institutions. At age 16, she first attempted suicide and the next 20 years she spent in and out of the institutions. At last, a caring doctor started treating her for extreme depression and panic disorder. Weened from strong medications she had taken all her life, at age 36, she emerged for the last time and started a rehabilitation program in the home of a volunteer married couple. There she met a fellow patient with whom she developed a romantic relationship. She also started a college degree. This followed with a long-term professional success in the field of mental health.

A Pittsburgh apartment superintendent loses his job and home when the apartment building where he lives and works at is suddenly destroyed by fire. Daniel and his family moves in with his brother but that doesn't last for long due to the two families not getting along with each other. The family moves from rundown hotels to homeless shelters as Daniel searches work as a electrician while his wife takes waitress jobs to try to make ends meet.

Michael Carlin, a teacher, has been having an affair with a much younger fellow teacher Carolyn Warmus. When his wife is murdered, the police suspect him due to inconsistencies in his alibi, and no evidence points to anyone else.