Ensemble cast of off-the-wall Warner Brothers characters, appearing in a wide variety of roles. Wakko, Yakko, and Dot Warner, are WB Studio creations who were just too "zany" to be of any use to the studio. Pinky and the Brain are two mice bent on world domination. Rita and Runt are a cat and dog team, who get into perilous situations every episode, put always seem to find time to sing a song. Bobby, Pesto, and Squit are the Goodfeathers, part of a New York mob of pigeons, who worship Martin Scorsese. Slappy the Squirrel is a late middle-age squirrel; she starred in a series of popular cartoons in the Golden Age. Buttons is a watch-dog, charged with watching the mischievous toddler, Mindy. Chicken Boo is a giant chicken trying to integrate into human society. Flavio and Marita are two urbane hippopotami.

Los Angeles County medical examiner Quincy routinely engages in police investigations.

An ancient prophecy is about to be fulfilled as a secret code brings the world to the edge of apocalypse.

一次例行的拖车任务将板牙带到了东京，在那里他被挑战与一个邪恶帮派首领及其忍者团队进行漂移风格的比赛。在他的朋友“龙”闪电麦昆和一些特殊改装的帮助下，板牙试图漂移获胜，成为拖车王板牙，所有漂移者的王。