Reviews the most intriguing applications of fractal analysis in neuroscience with a focus on current and future potential, limits, advantages, and disadvantages. Will bring an understanding of fractals to clinicians and researchers also if they do not have a mathematical background, and will serve as a good tool for teaching the translational applications of computational models to students and scholars of different disciplines. This comprehensive collection is organized in four parts:
(1) Basics of fractal analysis;
(2) Applications of fractals to the basic neurosciences;
(3) Applications of fractals to the clinical neurosciences;
(4) Analysis software, modeling and methodology.
Series: Springer Series in Computational Neuroscience

本手册是一本介绍羌塘高原常见种子植物的图文并茂的科普性读物。手册共收录羌塘高原常见的种子植物176种（含变种），每个种都配以彩色图片，列出中文学名、拉丁文学名、主要形态特征，以便于读者对照识别。尽可能地对每种植物在当地的利用方法和潜在用途，包括在畜牧业生产、医药、生态、观赏等方面，尤其是其在藏药中的用途，作了简要介绍。

- Presents the life's work of a Nobel Laureate and internationally recognised leader in the field
- Builds new bridges between physics and biology
- Provides a physical basis for Darwin's principle of natural selection
- Presents a new theory of information including semantics
This book presents a vivid argument for the almost lost idea of a unity of all natural sciences. It starts with the "strange" physics of matter, including particle physics, atomic physics and quantum mechanics, cosmology, relativity and their consequences (Chapter I), and it continues by describing the properties of material systems that are best understood by statistical and phase-space concepts (Chapter II). These lead to entropy and to the classical picture of quantitative information, initially devoid of value and meaning (Chapter III). Finally, "information space" and dynamics within it are introduced as a basis for semantics (Chapter IV), leading to an exploration of life and thought as new problems in physics (Chapter V).
Dynamic equations - again of a strange (but very general) nature - bring about the complex familiarity of the world we live in. Surprising new results in the life sciences open our eyes to the richness of physical thought, and they show us what can and what cannot be explained by a Darwinian approach. The abstract physical approach is applicable to the origins of life, of meaningful information and even of our universe.

《基因工程原理(上册)(第2版)》是在第一版的基础上，吸收了本学科的新进展，增加了大量的新内容，重新审订、编写而成。全书共十二章，分上下两册，书末附有基因工程名词术语解释及索引。《基因工程原理(上册)(第2版)》由三个有机联系的部分组成。第一部分论述基因工程赖以创立的理论及技术基础，重点介绍基因研究的发展及基因的现代概念;基因研究与基因工程的相互依赖关系;基因操作主要技术的基本原理;与基因克隆有关的上系列核酸酶的生化特性和在DNA重组中的应用等。第二部分由第四章至第八章组成，系《基因工程原理(上册)(第2版)》的核心。它详细地叙述了基因工程学所涉及的主要内容，包括各类分予克隆载体的构建、特点与应用;基因文库的构建、目的基因的分离与鉴定;克隆基因的表达与调控以及真核基因在大肠杆菌中表达的原理、方法及实例等。第三部分即《基因工程原理(上册)(第2版)》的后四章，主要论述基因工程实际应用方面的内容。它着重叙述高等植物及哺乳动物基因工程的研究目标、现状与进展，以及重组DNA技术在临床医学、农业生产、食品工业、化学制剂等若干重要领域的实际应用情况。《基因工程原理(上册)(第2版)》是一部有自己特色、体系新颖、基础理论与实际应用并重的基因工程学术专著。在内容的安排上注重科学性、先进性、系统性和条理性。

A groundbreaking book about how ancient DNA has profoundly changed our understanding of human history.
Geneticists like David Reich have made astounding advances in the field of genomics, which is proving to be as important as archeology, linguistics, and written records as a means to understand our ancestry.
In Who We Are and How We Got Here, Reich allows readers to discover how the human genome provides not only all the information a human embryo needs to develop but also the hidden story of our species. Reich delves into how the genomic revolution is transforming our understanding of modern humans and how DNA studies reveal deep inequalities among different populations, between the sexes, and among individuals. Provocatively, Reich’s book suggests that there might very well be biological differences among human populations but that these differences are unlikely to conform to common stereotypes.
Drawing upon revolutionary findings and unparalleled scientific studies, Who We Are and How We Got Here is a captivating glimpse into humankind—where we came from and what that says about our lives today.

Biochemistry Molecular Biology of Plants is a major contribution to the plant sciences literature, superbly edited by three distinguished scientists, Bob B. Buchanan, Wilhelm Gruissem, and Russell L. Jones, with contributions from more than 50 world-renowned scientists. With over 1,400 pages, 1,100 full-colour original drawings and 500 photographs this work qualifies, in the words of the Science reviewer, as:
"an essential reference for practicing plant biologists and for the increasing number of scientists from other disciplines who are entering the field of plant biology. To exploit fully the wealth of new information provided by the genome projects and to integrate the metabolic, regulatory, and signal transduction pathways of complex organisms, biologists will require a solid command of biochemistry and physiology. For this reason, the publication of Biochemistry Molecular Biology of Plants could not have come at a more opportune and auspicious time."
This book is meticulously organised and richly illustrated, useful both for teaching and for reference. The multi-authored work provides a contemporary view of its subject, including molecular biology, cell biology, and plant physiology, integrated around the themes of:



compartmentation
cell reproduction
energetics
metabolism
development Read the words of the reviewer in CELL:
"The great strength of this book is that it has integrated its three major components (molecular biology, cell biology, and plant biochemistry) in each of the 24 chapters, resulting in a comprehensive analysis of a multitude of specific topics."
Who should buy this spectacular new text?
Plant biologists and scientists in related fields
Professors in departments of plant biology, plant biochemistry, plant physiology, and related fields
Graduate and upper-level undergraduate students of plant biology
Researchers in the pharmaceutical, biotechnology, and agribusiness industries
A CD-ROM of all illustrative matter in the book is available separately.

Every student package automatically includes a CD-ROM and access to a website containing tutorials, molecular models, and more.
The long-awaited Fifth Edition of James D. Watson's classic text, Molecular Biology of the Gene, has been thoroughly revised and is published to coincide with the 50th anniversary of Watson and Crick's paper on the structure of the DNA double- helix.
Despite being completely updated, the new edition retains the distinctive character of earlier editions that made it the most widely used book in molecular biology. Twenty-one concise chapters, co-authored by five highly respected molecular biologists, provide current, authoritative coverage of a fast-changing discipline. The completely new art is printed in full colour for the first time.
Divided into four parts, the first (Genetics and Chemistry) begins with an overview of molecular biology, placing the discipline in historical context and introducing the basic chemical concepts that underpin our description of molecular biology today. The second part (Central Dogma) forms the heart of the book, describing in detail the basic mechanisms of molecular biology. The third part of the book (Regulation) deals with how gene expression is regulated - from the examination of basic mechanisms that regulate gene expression in bacterial and eukaryotic systems, to a description of how regulation of gene expression lies at the heart of the process of development. Recent findings from sequencing whole genomes of several animals have revealed that they all share essentially the same genes. The last chapter in the regulation section looks at how changes in gene regulation can account for how different animals can be made from the same genes. The final part of the book (Methods) deals with the techniques and methods used in molecular biology.
[Contents]
I. CHEMISTRY AND GENETICS.
1. The Mendelian View of the World.
2. Nucleic Acids Convey Genetic Information.
3. The Importance of Weak Chemical Interactions.
4. The Importance of High Energy Bonds.
5. Weak and Strong Bonds Determine Macromolecular Interactions.
II. CENTRAL DOGMA.
6. The Structures of DNA and RNA.
7. Chromatin and the Nucleosome.
8. The Replication of DNA.
9. The Mutability and Repair of DNA.
10. Homologous Recombination of DNA.
11. Site Specific Recombination and Transposition of DNA.
12. Mechanisms of Transcription.
13. The Processing of RNA.
14. Translation.
15. The Genetic Code.
III. REGULATION.
16. Gene Regulation in Prokaryotes.
17. Gene Regulation in Eukaryotes.
18. Gene Regulation in Development.
19. Comparative Genomics and the Evolution of Animal Diversity.
IV. METHODS.
20. Techniques of Molecular Biology.
21. Model Systems: Cells and Viruses.
[Features]
Early chapters on chemical and molecular interactions give a richer context to the material that follows and stress the importance of weak chemical interactions in biology.
The text has balanced coverage of prokaryotic and eukaryotic systems.
Important experiments and techniques relevant to chapter concepts are revealed in boxes in every chapter. These include recent techniques from the fields of genomics and bioinformatics.
Quantitative and critical thinking end-of-chapter questions allow students to apply their knowledge of the chapters key concepts.
An all new art programme features more than 750 line drawings in full colour. In addition, the art in the text has been integrated into animations on the accompanying CD-ROM and website.
The lively, incisive writing style that characterized earlier editions is once again a hallmark in the new edition.
Integrated media helps students better understand complex structures and molecular interactions. The CD-ROM and website offer animated tutorials, critical thinking exercises, and 3-D interactive molecular models in Chime.

In this classic, originally published 25 years ago and now reprinted with a new Afterword by the author on how he came to write the book, Judson tells the story of the birth and early development of molecular biology, in the US, the UK and France. In particular, the fascinating account of the remarkable golden period from the revelation of the double helix structure of DNA through to cracking the genetic code and solving the basic problems of how genes are regulated, is told largely in the words of the main players in the unfolding drama, all of whom were interviewed extensively by Judson in preparing this acclaimed volume. As well as the new Afterword that appears here for the first time, the current edition contains the material added by the author to the earlier "Expanded Edition" (CSHL Press 1996) on some of the principal figures involved, particularly Rosalind Franklin, together with the Afterword added at that time which sketches the further development of molecular biology into the era of recombinant DNA.

Mitochondria are tiny structures located inside our cells that carry out the essential task of producing energy for the cell. They are found in all complex living things, and in that sense, they are fundamental for driving complex life on the planet. But there is much more to them than that. Mitochondria have their own DNA, with their own small collection of genes, separate from those in the cell nucleus. It is thought that they were once bacteria living independent lives. Their enslavement within the larger cell was a turning point in the evolution of life, enabling the development of complex organisms and, closely related, the origin of two sexes. Unlike the DNA in the nucleus, mitochondrial DNA is passed down exclusively (or almost exclusively) via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to 'Mitochondrial Eve'. Mitochondria give us important information about our evolutionary history. And that's not all. Mitochondrial genes mutate much faster than those in the nucleus because of the free radicals produced in their energy-generating role.This high mutation rate lies behind our ageing and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer, through their involvement in precipitating cell suicide. Mitochondria, then, are pivotal in power, sex, and suicide. In this fascinating and thought-provoking book, Nick Lane brings together the latest research findings in this exciting field to show how our growing understanding of mitochondria is shedding light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. This understanding is of fundamental importance, both in understanding how we and all other complex life came to be, but also in order to be able to control our own illnesses, and delay our degeneration and death. 'An extraordinary account of groundbreaking modern science...The book abounds with interesting and important ideas.' Mark Ridley, Department of Zoology, University of Oxford

由伯特·荷尔多布勒编著的《超个体》是近10年来出版的最重要的科普著作之一。在《蚂蚁》一书出版18年后，这部新的著作将我们的知识扩展到了其他社会性的昆虫（包括蚂蚁、蜜蜂、黄蜂、白蚁），吸收了近20年最重要的研究发现。《超个体》是一个组织严密的集群，建立在利他主义的合作、复杂的沟通和劳动分工的基础之上。它代表了生物组织的一个基本阶段，介于普通组织和整个物种之间。正如作者所说的，对超个体的研究将使我们更深刻地理解各种进化水平之间是如何转换的，以及生命整体是如何从简单到复杂进化的。

Essential Cell Biology provides an accessible introduction to the fundamental concepts of cell biology. Its lively writing and exceptional illustrations make it the ideal textbook for a first course in cell and molecular biology. The text and figures are easy-to-follow, accurate, clear, and engaging for the introductory student. Molecular detail has been kept to a minimum in order to provide the reader with a cohesive, conceptual framework of the basic science that underlies our current understanding of biology. The Third Edition is thoroughly updated scientifically, yet maintains the academic level and size of the previous edition. The book is accompanied by a Media DVD-ROM with over 130 animations and videos, all the figures from the book, and a new self-test quizzing feature for students.

For nearly a quarter century, "Molecular Biology of the Cell" has been the leading cell biology textbook. This tradition continues with the new Fifth Edition, which has been completely revised and updated to describe our current, rapidly advancing understanding of cell biology. To list but a few examples, a large amount of new material is presented on epigenetics; stem cells; RNAi; comparative genomics; the latest cancer therapies; apoptosis (now its own separate chapter); and cell cycle control and the mechanics of M phase (now integrated into one chapter). The hallmark features of "Molecular Biology of the Cell" have been retained, such as its consistent and comprehensive art program, clear concept headings, and succinct section summaries. Additionally, in response to extensive feedback from readers, the Fifth Edition now includes several new features. It is now more portable. Chapters 1-20 are printed and Chapters 21-25, covering multicellular systems, are provided as PDF files on the free Media DVD-ROM which accompanies the book. And for the first time, "Molecular Biology of the Cell" now contains end-of-chapter questions. These problems, written by John Wilson and Tim Hunt, emphasize a quantitative approach and the art of reasoning from experiments, and they will help students review and extend their knowledge derived from reading the textbook. The Media DVD-ROM, which is packaged with every copy of the book, contains PowerPoint[registered] presentations with all of the figures, tables and micrographs from the text (available as JPEGs too). Also included is the Media Player, which plays over 125 movies - animations, videos, and molecular models - all with voice-over narration. A new reader-friendly feature is the integration of media codes throughout the text that link directly to relevant videos and animations. The Media DVD-ROM holds the multicellular systems chapters (21-25) of the text as well. By skillfully extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and thereby create a coherent framework through which readers may approach and enjoy this subject that is so central to all of biology. There is also a reference edition of "Molecular Biology of the Cell, Fifth Edition" (ISBN 978-0-8153-4111-6) that contains Chapters 1-25 entirely in printed format.

《普通高等教育"十一五"国家级规划教材:细胞生物学(第4版)》共17章，内容包括细胞的统一性与多样性、细胞生物学研究方法、细胞质膜、物质的跨膜运输、线粒体、叶绿体、细胞质基质与内膜系统、蛋白质分选与膜泡运输、细胞信号转导、细胞骨架、细胞核与染色质、核糖体、细胞周期与细胞分裂、细胞增殖调控与癌细胞、细胞分化与胚胎发育、细胞死亡、细胞衰老、细胞的社会联系等。《普通高等教育"十一五"国家级规划教材:细胞生物学(第4版)》共有图片370余幅，其中照片120余幅，全部插图均为作者自主设计、绘制，全部照片源自作者科研成果或授权使用。

这本科学家撰写的散文杰作，收集了古尔德在《自然史》杂志上发表的科学随想。作者在哈佛大学教生物学，是科学内行，又有历史家的眼光。他提出了一个问题：达尔文在确立了进化论之后，为什么迟了20年才发表？古尔德说，这是因为他清楚进化论的含义比一般人所意识到的更为离经叛道。

A major book about the future of the world, blending intellectual and natural history and field reporting into a powerful account of the mass extinction unfolding before our eyes
Over the last half a billion years, there have been five mass extinctions, when the diversity of life on earth suddenly and dramatically contracted. Scientists around the world are currently monitoring the sixth extinction, predicted to be the most devastating extinction event since the asteroid impact that wiped out the dinosaurs. This time around, the cataclysm is us. In The Sixth Extinction, two-time winner of the National Magazine Award and New Yorker writer Elizabeth Kolbert draws on the work of scores of researchers in half a dozen disciplines, accompanying many of them into the field: geologists who study deep ocean cores, botanists who follow the tree line as it climbs up the Andes, marine biologists who dive off the Great Barrier Reef. She introduces us to a dozen species, some already gone, others facing extinction, including the Panamian golden frog, staghorn coral, the great auk, and the Sumatran rhino. Through these stories, Kolbert provides a moving account of the disappearances occurring all around us and traces the evolution of extinction as concept, from its first articulation by Georges Cuvier in revolutionary Paris up through the present day. The sixth extinction is likely to be mankind's most lasting legacy; as Kolbert observes, it compels us to rethink the fundamental question of what it means to be human.

本书以普季岑和芬克尔斯泰因教授的讲稿为基础，吸纳生物物理学的最新成果，汇编成书，并经国内生物物理领域的资深学者精心翻译为中文。书中的25讲涵盖了蛋白质结构、折叠和功能的主要论题，论述了纤维状蛋白质、膜蛋白质和球状蛋白质的天然与变性状态，体现了下列特色：系统总结了数十年来全世界范围内蛋白质物理学、蛋白质结构和折叠原理研究方面取得的成果；略去了复杂的数学推导，通过轻松的语言，运用类比等叙述方式，将艰深的统计物理、热力学等理论知识形象生动地展现给读者；每讲中会适时地插入“质疑”和“答疑”部分，启发读者进一步思索相关问题，从而加深对蛋白质结构、折叠和功能机理的认识。
本书可以作为高年级本科生、研究生的教材和教学参考书，也可供其他研究者阅读参考，针对的专业除了生物物理、分子生物学、细胞生物学、遗传学等生命科学相关领域以外，还包括化学生物学、物理学等领域。

本书共分三篇，内容包括：“DNA功能与结构：阐明脱氧核糖核酸(遗传物质)的结构”、“RNA结构的功能：破解遗传密码，发现信使”、“蛋白质结构和功能：蛋白质分子是怎样工作的”。