在线阅读本书
For nearly a quarter century "Molecular Biology of the Cell" has been the leading cell biology textbook. This tradition continues with the new Fifth Edition, which has been completely revised and updated to describe our current, rapidly advancing understanding of cell biology. To list but a few examples, a large amount of new material is presented on epigenetics; stem cells; RNAi; comparative genomics; the latest cancer therapies; apoptosis (now its own separate chapter); and cell cycle control and the mechanics of M phase (now integrated into one chapter). The hallmark features of "Molecular Biology of the Cell" have been retained, such as its consistent and comprehensive art program, clear concept headings, and succinct section summaries.Additionally, in response to extensive feedback from readers, the Fifth Edition now includes several new features. It is now more portable. Chapters 1-20 are printed and Chapters 21-25, covering multicellular systems, are provided as pdf files on the free Media DVD-ROM which accompanies the book. And for the first time, "Molecular Biology of the Cell" now contains end-of-chapter questions. These problems, written by John Wilson and Tim Hunt, emphasize a quantitative approach and the art of reasoning from experiments, and - they will help students review and extend their knowledge derived from reading the textbook.The Media DVD-ROM, which is packaged with every copy of the book, contains PowerPoint[registered] presentations with all of the figures, tables and micrographs from the text (available as JPEGs too). Also included is the Media Player, which plays over 125 movies -animations, videos, and molecular models - all with voiceover narration. A new reader-friendly feature is the integration of media codes throughout the text that link directly to relevant videos and animations. The Media DVD-ROM holds the multicellular systems chapters (21-25) of the text as well. By skillfully extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and thereby create a coherent framework through which readers may approach and enjoy this subject that is so central to all of biology. There is also a reference edition of "Molecular Biology of the Cell, Fifth Edition" (ISBN 978-0-8153-4111-6) that contains Chapters 1-25 entirely in printed format.

分子生物学与分子遗传学领域正经历着日新月异的变化，每天都会出现新的数据，那些热门的研究进程，过去每隔数年才会出现新的见解和看法，现在只要几周或几个月。在过去几十年里，对广大教学者来说，Lewin的《基因》是一本十分优秀的教材，该书对分子生物学和分子遗传学进行了精彩的论述，内容涵盖了基因的结构、序列、组织和表达。最新版的Lewin《基因X》，拥有一支崭新的作者队伍，21位科学家根据各自的专业研究特长，对书中内容进行了修订和更新，以保证《基因X》是本领域最新颖全面的教材。《基因X》在内容上增加了一些新的章节，结构也进行了一些调整，使得全书各个主题在排列上更加富有逻辑性。另外许多章节也重新命名，和内容更加相符。新版中还包含了一些新的教学特色，便于学生在阅读本书过程中更好地学习；增加了在线学习导航，学生可以使用它对关键内容进行自我测试。
新版特色
 全新的第3章——分子生物学和基因工程方法，详细介绍了分子生物学实验技术的概念和实践。
 新加入的第8章——基因组进化，对于早期版本分散在各章节中的相关材料做了整合、扩展和更新，并介绍了一些新进展。
 第22章——mRNA的稳定性和定位，完全更新并重写，以包含更多的前沿内容。
 第30章——调控RNA和小RNA，特别引入了RNAi通路的相关内容。
 大量崭新的精美插图反映了相关领域的新进展，尤其是基因组结构和功能、表观遗传学，以及原核生物中非编码和小RNA的调控。