Science
The Immortal Life of Henrietta Lacks 豆瓣 Goodreads
The Immortal Life of Henrietta Lacks
作者: Rebecca Skloot 出版社: Crown Publishing Group 2010 - 2
Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.
Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.
Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia—a land of wooden slave quarters, faith healings, and voodoo—to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.
Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family—past and present—is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.
Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?
Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.
Complexity 豆瓣
作者: Mitchell M. Waldrop 出版社: Simon & Schuster 1992 - 1
In a rented convent in Santa Fe, a revolution has been brewing. The activists are not anarchists, but rather Nobel Laureates in physics and economics such as Murray Gell-Mann and Kenneth Arrow, and pony-tailed graduate students, mathematicians, and computer scientists down from Los Alamos. They've formed an iconoclastic think tank called the Santa Fe Institute, and their radical idea is to create a new science called complexity. These mavericks from academe share a deep impatience with the kind of linear, reductionist thinking that has dominated science since the time of Newton. Instead, they are gathering novel ideas about interconnectedness, coevolution, chaos, structure, and order - and they're forging them into an entirely new, unified way of thinking about nature, human social behavior, life, and the universe itself. They want to know how a primordial soup of simple molecules managed to turn itself into the first living cell - and what the origin of life some four billion years ago can tell us about the process of technological innovation today. They want to know why ancient ecosystems often remained stable for millions of years, only to vanish in a geological instant - and what such events have to do with the sudden collapse of Soviet communism in the late 1980s. They want to know why the economy can behave in unpredictable ways that economists can't explain - and how the random process of Darwinian natural selection managed to produce such wonderfully intricate structures as the eye and the kidney. Above all, they want to know how the universe manages to bring forth complex structures such as galaxies, stars, planets, bacteria, plants, animals, and brains. There are commonthreads in all of these queries, and these Santa Fe scientists seek to understand them. Complexity is their story: the messy, funny, human story of how science really happens. Here is the tale of Brian Arthur, the Belfast-born economist who stubbornly pushed his theories of economic ch
Principles of Neural Science 豆瓣 Goodreads
作者: Eric R. Kandel / James H. Schwartz 出版社: McGraw-Hill Medical 2000 - 1
This is the most authoritative introduction to the brain, its structure, function, development, and control of behavior available today. It presents both a comprehensive summary of the state of the science and a full discussion of historical issues in the study of the brain. Neuroanatomy, cell and molecular mechanisms, mechanisms, of signaling, and development are thoroughly described in the context of the cognitive approaches to behavior. Thoroughly revised, with a new full-color art program, this text was re-designed to be more user friendly. Also featured is an expanded treatment of the development of the nervous system, the genetic basis of neurological and psychiatric diseases, the cognitive neuroscience of perception, and icon channel mechanisms.
时间地图 豆瓣
作者: [美国] 大卫·克里斯蒂安 译者: 晏可佳 出版社: 上海社会科学院出版社 2007 - 1
《时间地图》将自然史与人类史综合成了一篇宏伟壮丽而又通俗易懂的叙述。这是一项伟大的成就,类似于17世纪伊萨克·牛顿运用匀速运动定律将地球与天体联系在一起的那种方式;甚至更接近于19世纪达尔所取得的成就,即用进化的过程来展现人类与其他生命形之间的联系。
这些书籍拓展了历史研究的地域与时间范围,表明早在1989年大卫·克里斯蒂安已经开始教材之际,克里斯蒂安不伟思索地说:“为什么不能从宇宙的起源讲起呢?”他的同事们当即请他讲述自己的观点。与其他那些把授课范围限制在世界史之内的历史学家不同,克里斯蒂安决定从宇宙本身讲起;在他开玩笑地将这项研究称为“大历史”的那一年,也曾有过犹豫,此时其他院系致力于各研究领域讲授不同课程的同事向他伸出了授助之手。
不论——科学的极限与极限的科学 豆瓣
作者: 巴罗(英国) 出版社: 上海科学技术出版公司 2001 - 1
本书是一本高级科普读物,它勾画了科学发展模式:当科学处于发展阶段时,会有许多令人激动的新发现、新公式和不同凡响的预言;当科学成熟时,科学本身越来越使人们坚信它能提供一切问题的答案;然而,当科学变老时会发生什么呢?科学到底能走多远?这正是本书所要展开的主题。