Molecular Cloning has served as the foundation of technical
expertise in labs worldwide for 30 years. No other manual has been
so popular, or so influential. Molecular Cloning, Fourth Edition,
by the celebrated founding author Joe Sambrook and new co-author,
the distinguished HHMI investigator Michael Green, preserves the
highly praised detail and clarity of previous editions and includes
specific chapters and protocols commissioned for the book from
expert practitioners at Yale, U Mass, Rockefeller University, Texas
Tech, Cold Spring Harbor Laboratory, Washington University, and
other leading institutions. The theoretical and historical
underpinnings of techniques are prominent features of the
presentation throughout, information that does much to help
trouble-shoot experimental problems.
For the fourth edition of this classic work, the content has
been entirely recast to include nucleic-acid based methods selected
as the most widely used and valuable in molecular and cellular
biology laboratories.
Core chapters from the third edition have been revised to
feature current strategies and approaches to the preparation and
cloning of nucleic acids, gene transfer, and expression analysis.
They are augmented by 12 new chapters which show how DNA, RNA, and
proteins should be prepared, evaluated, and manipulated, and how
data generation and analysis can be handled.
The new content includes methods for studying interactions
between cellular components, such as microarrays, next-generation
sequencing technologies, RNA interference, and epigenetic analysis
using DNA methylation techniques and chromatin immunoprecipitation.
To make sense of the wealth of data produced by these techniques, a
bioinformatics chapter describes the use of analytical tools for
comparing sequences of genes and proteins and identifying common
expression patterns among sets of genes.
Building on thirty years of trust, reliability, and authority,
the fourth edition of Molecular Cloning is the new gold
standard—the one indispensable molecular biology laboratory manual
and reference source.

《最年轻的科学:一个医学观察者的手记(汉英对照)》是刘易斯·托马斯的第三《最年轻的科学:一个医学观察者的手记(汉英对照)》，是他对于西方现代医学的发展史所作的最切近、最全面的观察。他看他父亲行医，自己学医，做实习医生，随军，做医生，研究，领导科研和教学，参与城市卫生管理与规划，服务于总统科学顾问委员会，观察大学、研究所和医院，体察护士的工作和生涯，甚至还受过伤、生过病。对于今天预备做医生的人，托马斯是无法取代，不可错过的。没有他，你的专业教育将是不完整、缺乏高度的。托马斯是不可方物，无以名之的。他是一个医生、病理学家、教育家、行政官员、诗人和散文家。一个人，如果兼作上述这些行当，他就是任何这些行当所不能局限和定义的。换句话说，如果他是这些，他就同时又不是这些。那就意味着，他已经达到了这样一个高度，他的话，是对于人类有着普遍意义的，即使在他谈论着高度专门的题目时，也是这样。

《发育原理》(第2版)简明扼要，概括性强，每章用不长的篇幅既系统阐述了发育原理又重点介绍了必要概念；选用了大量图解配合有关章节内容形象地解释发育原理和重要概念，并精心撰写了各章节的小结附于其后，对主要内容的展示起到了画龙点睛的作用；在编排体系上，内容衔接逻辑性强，因而易于讲授与学习；书后附有重要的术语，便于诀者对这些关键性概念的检索和理解。

《普通高等教育"十一五"国家级规划教材:发育生物学(第3版)》分为3篇共24章，全面、系统介绍了发育生物学的基础知识和基本理论，以及发育生物学的最新研究进展。第一篇“发育生物学基础”，讲述细胞命运的决定、细胞分化的分子机制、发育中的信号转导与网络调控、发育生物学模式生物、发育生物学研究技术等内容。第二篇“动物胚胎发育”，介绍从生殖细胞发生开始的整个动物胚胎发育和器官形成等发育事件及其调控原理。第三篇“发育生物学其他研究领域”，主要介绍干细胞生物学、发育机制的进化、发育可塑性与共生、植物的生长发育等内容。

《神经系统发育(原著第3版)(导读版•英文版)》由三位知名学者主笔，以现在和既往的重要实验与观察结果为例，对业已建立的和正在演变的神经发育原理进行广泛和基础的讨论。
《神经系统发育(原著第3版)(导读版•英文版)》按照个体发生的顺序组织内容。从出现神经原基开始，随后每一章节按神经发育事件出现的顺序组织：神经系统的模式建成和生长，神经元命运决定，轴突导向和靶点寻找，神经元存活与死亡，突触形成与发育的可塑性。在结构部分基本完成后，最后一章讨论了行为的出现。
新版的《神经系统发育》反映了通过新的分子遗传学和细胞生物学方法的应用取得的最新成果。丰富的彩色照片和原始绘图，辅以简明的叙述，使《神经系统发育(原著第3版)(导读版•英文版)》非常适合这一有趣领域的初涉者，包括高年级本科生、研究生和研究人员。

It is widely recognized that the neural basis of brain function can be fully understood only by integrating many disciplines at many levels. Studies os synaptic organization are bringing about a quiet revolution in achieving this goal, as documented by this unique book over the past 30 years. In this fifth edition, the results of the mouse and human genome projects are incorporated for the first time. Molecular biologists interested in functional genomics and proteomics of the brain will find answers here to the critical questions: what are the cell and circuit functions of gene products? Also for the first time, the reader is oriented to supporting neuroscience databases. Among the new advances covered are 2-photon confocal laser microscopy of dendrites and dendritic spines, biochemical analyses, and dual patch and multielectrode recordings, applied together with an increasing range of behavioural and gene-targeting methods. Leading experts in the best understood brain regions bring together the molecular, anatomical, functional, and behavioural data in authoritative integrated accounts.The chapters are organized in the same format, covering the neural elements, synaptic connections, basic circuits, physiology, neurotransmitters, neuromodulators, membrane properties, dendritic properties, and with a final section on how the circuits mediate specific behaviours. The uniform framework for each chapter enables the authors to higlight the principles that are common to all regions, as well as the adaptations unique to each, thus serving as a model for understanding the neural basis of behaviour.

Molecular Biology of the Cell is the classic in-depth text reference in cell biology. By extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and create a coherent framework through which non-expert readers may approach the subject. Written in clear and concise language, and beautifully illustrated, the book is enjoyable to read, and it provides a clear sense of the excitement of modern biology. Molecular Biology of the Cell sets forth the current understanding of cell biology (completely updated as of Autumn 2001), and it explores the intriguing implications and possibilities of the great deal that remains unknown.
The hallmark features of previous editions continue in the Fourth Edition. The book is designed with a clean and open, single-column layout. The art program maintains a completely consistent format and style, and includes over 1,600 photographs, electron micrographs, and original drawings by the authors. Clear and concise concept headings introduce each section. Every chapter contains extensive references. Most important, every chapter has been subjected to a rigorous, collaborative revision process where, in addition to incorporating comments from expert reviewers, each co-author reads and reviews the other authors' prose. The result is a truly integrated work with a single authorial voice.</P>

什么是生命的秩序？达尔文一生所求的关键化石为何始终缺失？每次生命大爆发之前，都有大规模物种灭绝降临，在生命的轮回中大灭绝究竟扮演了什么角色？
作者艾崔奇为读者扫清了知识的迷障，他精准地把握了生命演化的脉搏，从跨度数十亿年的重要化石中寻找启示。生物演化并不像达尔文设想的那样是缓慢而渐进的变化过程，艾崔奇揭示：在大规模物种灭绝发生之前，物种都不会发生任何显著的变化。这一生命的律动，正如地球上古老动植物化石记录的那样，被认为是当下对演化最为合理的描述。

神经元（神经细胞）是构成神经系统的基石，对神经元各个方面的深入、彻底的理解对于我们从各个层次对神经系统进行分析都是十分必要的。本书论述神经细胞的形态学、生物化学、生物物理学基础知识，这些知识正迎合了相关专业的大学生、研究生、科研人员的需要。
2000年诺贝尔生理医学奖获得者Eric R.Kandel盛赞此书：“凭着对神经生理学的独到的、富有创见的阐述，这本书填补了一个亟需填补的空白。
行文清晰，尤其是插图经过了精心设计，图示精美。
每一章的编写才均为该令域的权威和学科带头人。
被专家誉为“神经科学家书架上的必备书”。

Every student package automatically includes a CD-ROM and access to a website containing tutorials, molecular models, and more.
The long-awaited Fifth Edition of James D. Watson's classic text, Molecular Biology of the Gene, has been thoroughly revised and is published to coincide with the 50th anniversary of Watson and Crick's paper on the structure of the DNA double- helix.
Despite being completely updated, the new edition retains the distinctive character of earlier editions that made it the most widely used book in molecular biology. Twenty-one concise chapters, co-authored by five highly respected molecular biologists, provide current, authoritative coverage of a fast-changing discipline. The completely new art is printed in full colour for the first time.
Divided into four parts, the first (Genetics and Chemistry) begins with an overview of molecular biology, placing the discipline in historical context and introducing the basic chemical concepts that underpin our description of molecular biology today. The second part (Central Dogma) forms the heart of the book, describing in detail the basic mechanisms of molecular biology. The third part of the book (Regulation) deals with how gene expression is regulated - from the examination of basic mechanisms that regulate gene expression in bacterial and eukaryotic systems, to a description of how regulation of gene expression lies at the heart of the process of development. Recent findings from sequencing whole genomes of several animals have revealed that they all share essentially the same genes. The last chapter in the regulation section looks at how changes in gene regulation can account for how different animals can be made from the same genes. The final part of the book (Methods) deals with the techniques and methods used in molecular biology.
[Contents]
I. CHEMISTRY AND GENETICS.
1. The Mendelian View of the World.
2. Nucleic Acids Convey Genetic Information.
3. The Importance of Weak Chemical Interactions.
4. The Importance of High Energy Bonds.
5. Weak and Strong Bonds Determine Macromolecular Interactions.
II. CENTRAL DOGMA.
6. The Structures of DNA and RNA.
7. Chromatin and the Nucleosome.
8. The Replication of DNA.
9. The Mutability and Repair of DNA.
10. Homologous Recombination of DNA.
11. Site Specific Recombination and Transposition of DNA.
12. Mechanisms of Transcription.
13. The Processing of RNA.
14. Translation.
15. The Genetic Code.
III. REGULATION.
16. Gene Regulation in Prokaryotes.
17. Gene Regulation in Eukaryotes.
18. Gene Regulation in Development.
19. Comparative Genomics and the Evolution of Animal Diversity.
IV. METHODS.
20. Techniques of Molecular Biology.
21. Model Systems: Cells and Viruses.
[Features]
Early chapters on chemical and molecular interactions give a richer context to the material that follows and stress the importance of weak chemical interactions in biology.
The text has balanced coverage of prokaryotic and eukaryotic systems.
Important experiments and techniques relevant to chapter concepts are revealed in boxes in every chapter. These include recent techniques from the fields of genomics and bioinformatics.
Quantitative and critical thinking end-of-chapter questions allow students to apply their knowledge of the chapters key concepts.
An all new art programme features more than 750 line drawings in full colour. In addition, the art in the text has been integrated into animations on the accompanying CD-ROM and website.
The lively, incisive writing style that characterized earlier editions is once again a hallmark in the new edition.
Integrated media helps students better understand complex structures and molecular interactions. The CD-ROM and website offer animated tutorials, critical thinking exercises, and 3-D interactive molecular models in Chime.

What separates your mind from an animal's? Maybe you think it's your ability to design tools, your sense of self, or your grasp of past and future – all traits that have helped us define ourselves as the planet's preeminent species. But in recent decades, these claims have been eroded, or even disproven, by a revolution in the study of animal cognition: take the octopuses that use coconut shells as tools; the elephants that classify humans by age, gender, and language; or Ayumu, the young male chimpanzee at Kyoto University whose flash memory puts that of humans to shame. Based on research involving crows, dolphins, parrots, sheep, wasps, bats, whales, and of course chimpanzees and bonobos, Frans de Waal demonstrates that we have grossly underestimated both the scope and the depth of animal intelligence. He offers a firsthand account of how science has stood traditional behaviorism on its head by revealing how smart animals really are.

《从生态学透视生命系统的设计、运作与演化:生态、遗传和进化通过生殖的融合》系统地介绍了生态学的发展历史、不同尺度的生态学理论，包括模型、稳定性、可塑性、生态系统稳态转化、植被地理格局与演化、基因组进化、动植物生殖及"性"演化、生命的地质历史演化等。重点探讨了生命系统的设计、运作与进化等当前生命科学领域的热点问题。

序言
前言
第一章数学生态学稳定性理论与方法的若干问题
§·生态数学建模
§·环境分析
§·生态学中的稳定性问题
§·数学生态学中的稳定性问题
第二章单种群的稳定性
§·单种群连续性模型及其平衡状态的稳定性
§·时滞因素和种群平衡状态的稳定性
§·随机扰动对种群稳定性的影响
§·随机扰动与Logisti增长
§·种群的平均寿命
§·确定性模型和随机性模型
§·生物资源的可持续利用（一）
§·进化稳定对策
§·集合种群的稳定性
第三章种群的离散模型
§·世代不重叠种群模型
§·差分方程的周期解和混沌现象
§·具年龄结构的种群离散模型
§·Leslie算子的谱性质和渐近性质
§·Leslie模型中稳定解的分类
§·改进的Leslie模型——用恒定性方法处理变异性
§·改进的Leslie模型——分块结构在年龄组内处理变异性
§·依赖时间的各种修改渐近性态中的有限不确定性
§·依赖密度的修改非线性使渐近性态相异
§·生物资源的可持续利用（二）
第四章两种群相互作用的数学模型
§·两种群相互作用数学模型
§·Lotk-Volterr两种群模型及其稳定性
§·竞争系统
§·互利系统
§·捕食—被食系统的稳定性与极限环
§·捕食—被食系统的非线性性质
§·KоЛMоГороВ一般模型
§·具时滞的两种群模型的稳定性
§·两种群相互作用的离散模型
§·生物资源的可持续利用（三）
§·栖息地破坏与捕食一被食集合种群系统灭绝
第五章n种群生物群落
§·群落结构图与群落矩阵
§·LotkVolterr模型和生态平衡方程
§·稳定矩阵和可行平衡的全局稳定性
§·种内自调节机制对种间相互作用的影响
§·矩阵流图
§·保守系统的稳定性
§·定性稳定性和符号稳定性
§·“黑自”检验和符号稳定性准则
§·群落矩阵理论与应用
§·n种群生物群落的控制问题
§·生物群落的生态稳定性和生态稳定域
第六章具有垂直结构的群落的营养链和稳定性
§·具垂直结构的生物群落和营养链
§·营养链模型中的平衡状态及其稳定性
§·有限链稳定的条件
§·推广的营养链系统的稳定性
§·JЛялунов函数及营养链的稳定性
§·分叉的营养链
§·营养链的生态稳定性
§·开放链和部分封闭链中的周期形式
§·银泉生态系统的稳定性
第七章生态位的镶嵌与具水平结构的群落的稳定性
§·生态位概念和竞争动力学方程
§·竞争系数的其他表示
§·研究竞争矩阵的线性规划方法
§·评估值的算法
§·正的和部分为正的平衡状态
§·Volterr方程的频率形式
§·具水平结构的群落模型的极值性质
§·具水平结构群落模型极值的解释Mrthur严密隔离原则
第八章空间分布的生态系统的稳定性
§·迁徙能使群落稳定吗
§·各向异性环境中的迁徙
§·研究迁徙效应的小参数方法
§·空间分布群落的扩散模型与扩散不稳定性
第九章生态系统模型的稳定性与复杂性
§·生物群落稳定性与复杂性的关系
§·森林昆虫群落生态稳定的参数基础
§·生态系统的生态稳定性
§·生物群落的持续生存
第十章随机环境中生物群落的稳定性
§·随机模型的建立
§·极值条件下的种群
§·Logisti种群随机模型
§·种群大小的临界值问题和三禁领地的估计
§·多平衡状态种群的性质
§·随机环境中竞争群落的退化
§·随机环境中捕食一被食系统的稳定性
§·随机环境中生物群落的稳定性
参考文献

The Phylogenetic Handbook is a broad, hands on guide to theory and practice of nucleotide and protein phylogenetic analysis. This second edition includes six new chapters, covering topics such as Bayesian inference, tree topology testing and the impact of recombination on phylogenies, as well as a detailed section on molecular adaptation. The book has a stronger focus on hypothesis testing than the previous edition, with more extensive discussions on recombination analysis, detecting molecular adaptation and genealogy-based population genetics. Many chapters include elaborate practical sections, which have been updated to introduce the reader to the most recent versions of sequence analysis and phylogeny software, including BLAST, FastA, Clustal, T-coffee, Muscle, DAMBE, Tree-puzzle, Phylip, MEGA, PAUP*, IQPNNI, CONSEL, ModelTest, Prottest, PAML, HYPHY, MrBayes, BEAST, LAMARC, SplitsTree, and RDP. Many analysis tools are described by their original authors, resulting in clear explanations that constitute an ideal teaching guide for advanced-level undergraduate and graduate students.

从组学的生物时代开始，科学家一直追求的是降低基因组规模实验的复杂性，以便于了解其蕴含的基本生物学原理。在《蛋白质网络与途径分析》这本书中，专家从业人员汇编了函数数据分析的方法，经常被称为系统生物学，它被应用于药物研发、医学和基础医学领域的研究中。本书分为三部分：1)对蛋白质、化合物和基因之间相互作用的阐述；2)介绍了网络、相互作用组和本体论研究中常用的分析工具；3)函数分析的应用范围。作为非常著名的《分子生物学方法》系列丛书之一，本书提供了详细的说明，并且为动手实践提供了建议。
权威和前沿的《蛋白质网络与途径分析》既阐明了生物实验室实验方法，又介绍了相关计算工具，涵盖了这个令人着迷的新兴领域中大多数的问题。本书的作者(巴斯)Nikolsky博士，GeneGo公司总裁，在生命科学领域有着数十年的工作经验。

这是一个关于你自身的故事。你体内的故事——。
人的细胞数量，约为37兆2千亿个。
细胞们在名为身体的世界中，今天也精神满满、无休无眠地在工作着。
运送着氧气的红细胞，与细菌战斗的白细胞……！这里，有着细胞们不为人知的故事。

A fascinating history--. Literate and authoritative--.Marvelously exciting. -- The New York Times Book Review
Jonathan Weiner, winner of the Pulitzer Prize for The Beak of the Finch , brings his brilliant reporting skills to the story of Seymour Benzer, the Brooklyn-born maverick scientist whose study of genetics and experiments with fruit fly genes has helped revolutionize or knowledge of the connections between DNA and behavior both animal and human.
How much of our fate is decided before we are born? Which of our characteristics is inscribed in our DNA? Weiner brings us into Benzer's Fly Rooms at the California Institute of Technology, where Benzer, and his asssociates are in the process of finding answers, often astonishing ones, to these questions. Part biography, part thrilling scientific detective story, Time, Love, Memory forcefully demonstrates how Benzer's studies are changing our world view--and even our lives.

In this classic, originally published 25 years ago and now reprinted with a new Afterword by the author on how he came to write the book, Judson tells the story of the birth and early development of molecular biology, in the US, the UK and France. In particular, the fascinating account of the remarkable golden period from the revelation of the double helix structure of DNA through to cracking the genetic code and solving the basic problems of how genes are regulated, is told largely in the words of the main players in the unfolding drama, all of whom were interviewed extensively by Judson in preparing this acclaimed volume. As well as the new Afterword that appears here for the first time, the current edition contains the material added by the author to the earlier "Expanded Edition" (CSHL Press 1996) on some of the principal figures involved, particularly Rosalind Franklin, together with the Afterword added at that time which sketches the further development of molecular biology into the era of recombinant DNA.

《蛋白质物理》是一部蛋白质物理学研究领域的系统性著作，由享誉世界的俄罗斯科学家A.V.芬克尔施泰因和O.B.普季岑根据其为俄罗斯科学院和莫斯科大学的学生讲授蛋白质物理课程时的讲义撰写而成，具有很高的理论和学术价值。《蛋白质物理》内容广泛，包括了蛋白质的结构分类、变性与折叠、结构预测与设计等几个部分，其主旨是以物理学（特别是统计物理和热力学）的观点和方法来研究与蛋白质相关的问题。《蛋白质物理》循序渐进，深入浅出，不仅以简明易懂的语言和简繁适当的数学估算介绍了与蛋白质相关的基础问题，而且对本领域中的重点研究问题都高屋建瓴地予以严谨的分析和讨论，在研究思想上有很强的指导性和启发性。《蛋白质物理》英文版已在美、英、德等国多所大学采用为相关课程的教材。

1．《凤凰卫视》“开卷八分钟”梁文道专题报道
梁文道：如果它（植物）真的能够感知到这个世界，那整个我们人类的生活会改变的，我们跟植物的关系会彻底被改变掉......
2．世界科普杂志第一品牌《科学美国人》出品、2012亚马逊十佳科学图书、《自然》《华尔街日报》等大力推荐
《科学美国人》：美国历史最长的、一直连续出版的杂志，也是著名的《科学》（Science）的姊妹刊。到目前，有151位诺贝尔奖得主撰稿。每个月约有555,000份国内（美国）发行量，以及90,000份国际发行量，为全球科普杂志第一品牌。
3． 一个只有宁静心灵才能倾听的世界：植物会看、会闻、会触摸、有记忆、能定位
本书带领我们进入不同种类的植物生活，吸引我们将其与人类的感觉相对比，结果发现我们与向日葵、橡树之间的共同点远远比我们以为的多得多。
4权威科普作家捍卫科学，探讨生命之美但不妖魔化
本书作者是专业的植物学家，和部分介于科学和伪科学之间的身心灵图书不同，作者固守科学领域，引领读者在科学的范围内重新考量植物。
5本书为小开本精装、赠送折叠双开封面，30余张精美插图，展示精美的植物世界。