From the prize-winning author of Reasons to be Cheerful comes a story about the ebb and flow of female friendship over half a lifetime

'A true gift of a novel, I utterly adored it. For as long as I could make it last, the world just felt a bit nicer' Meg Mason

'Stibbe turns out more perfect, sharp, unique sentences than anyone else' Caitlin Moran

'Stibbe has an extraordinary gift' Marian Keyes

'Nina Stibbe makes being funny look easy, but that's just because she's very, very good at it' Clare Chambers
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Susan and Norma have been best friends for years, at first thrust together by force of circumstance (a job at The Pin Cushion, a haberdashery shop in 1990s Leicestershire) and then by force of character (neither being particularly inclined to make friends with anyone else). But now, thirty years later, faced with a husband seeking immortality and Norma out of reach on a wave of professional glory, Susan begins to wonder whether she has made the right choices about life, love, work, and, most importantly, friendship.

Nina Stibbe's new novel is the story of the wonderful and sometimes surprising path of friendship: from its conspiratorial beginnings, along its irritating wrong turns, to its final gratifying destination.
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'Nina Stibbe's very funny novels are full of charm, and her latest brilliantly captures the mordant humour of British suburban life' Evening Standard

'I absolutely loved every single page of it! I honestly think it's the funniest thing she's ever written' Garth Jennings

'I'm not surprised to see that Stibbe's writing has been compared to Jane Austen's' Emma Healey

'I am already longing for Nina Stibbe's next book' Observer

'Stibbe is one of the all-time greats' Daisy Buchanan

'Clever and funny, it takes a sharp look at the intricacies of marriage, friendship, work and driving. As with all Stibbe's writing there is a pleasingly perfect balance of wisdom with jokes' Cathy Rentzenbrink

'Nina Stibbe is not just very funny but absolutely life-affirming' Jenny Colgan

'For beautifully funny and well-observed comic writing, Nina Stibbe is your go-to author. In her latest release, a tale of lifelong friendship between Susan and Norma, she explores the mistakes, rivalries and love we all experience in life' Stylist

'One of the great comic writers of our time' Irish Times

NAMED A MOST ANTICIPATED BOOK BY The Millions, Harper's Bazaar, New York Magazine, LitHub, AV Club, and more

In a village in a medieval fiefdom buffeted by natural disasters, a motherless shepherd boy finds himself the unlikely pivot of a power struggle that puts all manner of faith to a savage test, in a spellbinding novel that represents Ottessa Moshfegh’s most exciting leap yet

Little Marek, the abused and delusional son of the village shepherd, never knew his mother; his father told him she died in childbirth. One of life’s few consolations for Marek is his enduring bond with the blind village midwife, Ina, who suckled him when he was a baby, as she did so many of the village’s children. Ina’s gifts extend beyond childcare: she possesses a unique ability to communicate with the natural world. Her gift often brings her the transmission of sacred knowledge on levels far beyond those available to other villagers, however religious they might be. For some people, Ina’s home in the woods outside of the village is a place to fear and to avoid, a godless place. 
 
Among their number is Father Barnabas, the town priest and lackey for the depraved lord and governor, Villiam, whose hilltop manor contains a secret embarrassment of riches. The people’s desperate need to believe that there are powers that be who have their best interests at heart is put to a cruel test by Villiam and the priest, especially in this year of record drought and famine. But when fate brings Marek into violent proximity to the lord’s family, new and occult forces upset the old order. By year’s end, the veil between blindness and sight, life and death, the natural world and the spirit world, will prove to be very thin indeed.

One of the most important and blazingly original writers of his generation, George Saunders is an undisputed master of the short story, and Tenth of December is his most honest, accessible, and moving collection yet.

In the taut opener, “Victory Lap,” a boy witnesses the attempted abduction of the girl next door and is faced with a harrowing choice: Does he ignore what he sees, or override years of smothering advice from his parents and act? In “Home,” a combat-damaged soldier moves back in with his mother and struggles to reconcile the world he left with the one to which he has returned. And in the title story, a stunning meditation on imagination, memory, and loss, a middle-aged cancer patient walks into the woods to commit suicide, only to encounter a troubled young boy who, over the course of a fateful morning, gives the dying man a final chance to recall who he really is. A hapless, deluded owner of an antiques store; two mothers struggling to do the right thing; a teenage girl whose idealism is challenged by a brutal brush with reality; a man tormented by a series of pharmaceutical experiments that force him to lust, to love, to kill—the unforgettable characters that populate the pages of Tenth of December are vividly and lovingly infused with Saunders’s signature blend of exuberant prose, deep humanity, and stylistic innovation.

Writing brilliantly and profoundly about class, sex, love, loss, work, despair, and war, Saunders cuts to the core of the contemporary experience. These stories take on the big questions and explore the fault lines of our own morality, delving into the questions of what makes us good and what makes us human.

Unsettling, insightful, and hilarious, the stories in Tenth of December —through their manic energy, their focus on what is redeemable in human beings, and their generosity of spirit—not only entertain and delight; they fulfill Chekhov’s dictum that art should “prepare us for tenderness.”
Advance praise for Tenth of December

“ Tenth of December shows George Saunders at his most subversive, hilarious, and emotionally piercing. Few writers can encompass that range of adjectives, but Saunders is a true original—restlessly inventive, yet deeply humane.”—Jennifer Egan, Pulitzer Prize–winning author of A Visit from the Goon Squad

“George Saunders is a complete original, unlike anyone else, thank god—and yet still he manages to be the rightful heir to three other complete American originals—Barthelme (the lyricism, the playfulness), Vonnegut (the outrage, the wit, the scope), and Twain (the common sense, the exasperation). There is no author I recommend to people more often—for ten years I’ve urged George Saunders onto everyone and everyone. You want funny? Saunders is your man. You want emotional heft? Saunders again. You want stories that are actually about something—stories that again and again get to the meat of matters of life and death and justice and country? Saunders. There is no one better, no one more essential to our national sense of self and sanity.”—Dave Eggers, author of A Hologram for the King
Praise for George Saunders

“Not since Twain has America produced a satirist this funny.”—Zadie Smith

“George Saunders makes the all-but-impossible look effortless. We’re lucky to have him.”—Jonathan Franzen

“An astoundingly tuned voice—graceful, dark, authentic, and funny—telling just the kinds of stories we need to get us through these times.”—Thomas Pynchon

In this moving and enormously entertaining debut novel, longtime romantic partners Kathryn and Chris experiment with an open relationship and reconsider everything they thought they knew about love.

After nine years together, Kathryn and Chris have the sort of relationship most would envy. They speak in the shorthand they have invented, complete one another’s sentences, and help each other through every daily and existential dilemma. But, as content as they are together, an enduring loneliness continues to haunt the dark corners of their relationship. When Chris tells Kathryn about his feelings for Emily, a vivacious young woman he sees often at the Laundromat, Kathryn encourages her boyfriend to pursue this other woman—certain that her bond with Chris is strong enough to weather a little side dalliance.

Next Year, For Sure tracks the tumultuous, revelatory, and often very funny year that follows. When Chris’s romance with Emily evolves beyond what anyone anticipated, both Chris and Kathryn are invited into Emily’s communal home, where Kathryn will discover new possibilities of her own. In the confusions, passions, and upheavals of their new lives, both Kathryn and Chris are forced to reconsider their past and what they thought they knew about love.

Offering a luminous portrait of a relationship from two perspectives, Zoey Leigh Paterson has written an empathic, beautiful, and tremendously honest novel about a great love pushed to the edge. Deeply poignant and hugely entertaining, Next Year, For Sure shows us what lies at the mysterious heart of relationships, and what true openness and transformation require.

Victor Bayne, the psychic half a PsyCop team, is a gay medium who's more concerned with flying under the radar than in making waves. He hooks up with Jacob Marks, a non-psychic (or "Stiff") from an adjacent precinct and it seems like his dubious luck has improved, when a serial killer with a gruesome M.O. surfaces--and no one agrees what he looks like. Explicit gay content.

"Engrossing...Epic" (The New York Times Book Review) · "Transporting" (Washington Post) · "Propulsive" (Oprah Daily) · "Surreal and sprawling" (NPR) · "An absolute must-read" (BuzzFeed) · "Radiant" (BookPage)

"Engulfing, bighearted, and heartbreaking.” —Ann Patchett

A New York Times Book Review Editors' Choice

A dazzling debut novel set against the backdrop of the Chinese Exclusion Act, about a Chinese girl fighting to claim her place in the 1880s American West

Daiyu never wanted to be like the tragic heroine for whom she was named, revered for her beauty and cursed with heartbreak. But when she is kidnapped and smuggled across an ocean from China to America, Daiyu must relinquish the home and future she imagined for herself. Over the years that follow, she is forced to keep reinventing herself to survive. From a calligraphy school, to a San Francisco brothel, to a shop tucked into the Idaho mountains, we follow Daiyu on a desperate quest to outrun the tragedy that chases her. As anti-Chinese sentiment sweeps across the country in a wave of unimaginable violence, Daiyu must draw on each of the selves she has been—including the ones she most wants to leave behind—in order to finally claim her own name and story.

At once a literary tour de force and a groundbreaking work of historical fiction, Four Treasures of the Sky announces Jenny Tinghui Zhang as an indelible new voice. Steeped in untold history and Chinese folklore, this novel is a spellbinding feat.

No one wants what no one wants.
And how do we even know what we want? How do we know we’re ready to take it?
Edie is stumbling her way through her twenties―sharing a subpar apartment in Bushwick, clocking in and out of her admin job, making a series of inappropriate sexual choices. She is also haltingly, fitfully giving heat and air to the art that simmers inside her. And then she meets Eric, a digital archivist with a family in New Jersey, including an autopsist wife who has agreed to an open marriage―with rules.
As if navigating the constantly shifting landscapes of contemporary sexual manners and racial politics weren’t hard enough, Edie finds herself unemployed and invited into Eric’s home―though not by Eric. She becomes a hesitant ally to his wife and a de facto role model to his adopted daughter. Edie may be the only black woman young Akila knows.

Stories of a young man finding his place among family and community in Houston, from a powerful, emerging American voice.
In the city of Houston - a sprawling, diverse microcosm of America - the son of a black mother and a Latino father is coming of age. He's working at his family's restaurant, weathering his brother's blows, resenting his older sister's absence. And discovering he likes boys.
This boy and his family experience the tumult of living in the margins, the heartbreak of ghosts, and the braveries of the human heart. The stories of others living and thriving and dying across Houston's myriad neighborhoods are woven throughout to reveal a young woman's affair detonating across an apartment complex, a rag-tag baseball team, a group of young hustlers, the aftermath of Hurricane Harvey, a local drug dealer who takes a Guatemalan teen under his wing, and a reluctant chupacabra.
Bryan Washington's brilliant, viscerally drawn world leaps off the page with energy, wit, and the infinite longing of people searching for home. With soulful insight into what makes a community, a family, and a life, Lot is about love in all its unsparing and unsteady forms.

Subway Series follows Tina, a frustrated sixteen-year-old city girl whose affections are divided between two guys. The problem is, one has an out of town girlfriend and the other is a complete jerk. Add to that a bitchy adversary whom she once called a friend who’s out to humiliate her, and now confused Tina doesn’t know which way to turn.

Language opens up our world, and in the same instant, limits it. What does it mean to exist in a language that was never meant for you to speak? Why are we missing certain words? How can we talk about our communal problems without fuelling them? What does it actually mean to speak freely?
As a writer and activist fighting for equality, K�bra G�m�say has been thinking about these questions for many years. In this book she explores how language shapes our thinking and determines our politics. She shows how people become invisible as individuals when they are always seen as part of a group, and the way those in the minority often have to expend energy cleaning up the messy thinking of others. But she also points to how we might shape conversations to allow for greater ambiguity and individuality, how arguments might happen in a space of learning and vulnerability without sacrificing principles - how we might all be able to speak freely.

A war is brewing. As the crown prince of Erya, it’s only natural that Caelan is sent on a secret diplomatic mission to support one of the kingdom’s allies. With his advisor, his bodyguard, and his best friend as traveling companions, what could go wrong?
Everything.
Everything goes wrong.
Now they are on the run, dodging assassins, setting secret meetings, and even making deals with a sleeping god.
So, this is probably a really bad time to cave to feelings he’s been fighting for his best friend. But Drayce has owned his heart for more years than he can count and if he’s going to die, shouldn’t he have just one kiss?
The fate of the world is on the line, and only Caelan holds the power to save them all.
Steal the Wind

精彩无比的一战经典之作，普利策奖委员会也为之“绕道”颁奖。
作者巴巴拉·塔奇曼被誉为“历史学者中的艺术家”，她的写作，令人沉浸、着迷。
是什么让世界踏进这场“不可能”发生的战争？肯尼迪总统从中汲取历史教训化解美苏危机。
【编辑推荐】
★ 普利策奖获奖经典作品，以精彩笔法展现帝国时代的终结战“一战”是如何开启并迅速陷入僵局，叩问是什么让帝王、政客和将领踏进这场“不可能”发生的战争，影响冷战高潮时期美、英等国决策者，对当今世界同样具有深刻的启发意义。
★ 以充满悬疑感的叙事手法和极富文学性的笔触还原历史场景，真正让人身临其境；深入挖掘信件、电报、日记甚至情书等资料，带读者走入时人内心，用极为人性的笔法刻画了一个个充满缺陷的决策者。
★ 威廉·夏伊勒、费正清、肯尼迪总统，《纽约时报》、《华尔街日报》、《纽约客》、《卫报》等盛赞推荐，普利策奖得主、著名历史学者罗伯特·马西专文导读。
★ 精选42幅一战关键人物和战时场景的珍贵照片；全新绘制10幅关键战役的作战地图。
★ 梁文道、刘瑜、熊培云、许知远联袂主编——“理想国译丛”（MIRROR）系列之一（029）——保持开放性的思想和非功利的眼睛，看看世界的丰富性与复杂性。
【名家推荐】
当代最佳书籍之一……全书从头到尾都吸引着我。
——威廉·夏伊勒，《第三帝国的兴亡》作者
《八月炮火》推出后立即洛阳纸贵，空前成功，书评争相推介，口碑迅速传开，吸引了成千上万的读者一睹为快。肯尼迪总统特别订了一本送给当时的英国首相麦克米伦，他的阅读心得是：当代政治家必须尽可能避免陷入1914年8月大战的陷阱。普利策奖捐款人已立下规章禁止颁发历史类奖项给主题与美国无关的著作，但是委员会还是找到名目，颁给作者塔奇曼“非虚构类奖”。《八月炮火》让作者一举成名，她的作品深入人心且文笔流畅优雅，但是大部分的读者只需要知道这本新书的作者是“巴巴拉·塔奇曼”这块金字招牌。
——罗伯特·马西，历史学者，凭《彼得大帝》获普利策奖
大约在十多年前，我看到了巴巴拉·塔奇曼的著作《八月炮火》，初翻几页，就深深被作者气势恢宏却又细致入微的写作方法吸引住了。……她讲究遣词用句，既要文字言之成理，又要读者读之有味；她极注重营造气氛，让读者身临其境。她的书，潇洒精彩，干净利落，没有赘语，如同卡拉瓦乔式的洞察细腻和落笔精准，也有卡拉瓦乔的不拘一格。……
当下中国出版界，各类粗制滥造的历史读物比比皆是，生动严谨的良心作品却是凤毛麟角，塔奇曼的著作，为那些热衷“编写”历史的作者提供了最好的借鉴。
——姜鸣，历史学者
在大战（一战）爆发前夕，欧洲国家绝大多数的知识分子、金融家与企业主，都没有意识到他们与即将爆发的巨大危机只有一尺之隔，他们对于政治领袖与军事谋略家加诸于自己的战争浩劫风险浑然不觉。
《八月炮火》一书点出了许多让人深思的历史吊诡与荒谬。一批深谙治国之术与权力均衡游戏的统治精英，他们机关算尽，最后却无法避免让自己成为历史悲剧中的主角；他们精心布置的军事盟约与政治承诺，最后却成为冲突升高过程中的重力加速器。
—— 朱云汉，“中研院”院士，台湾大学政治系教授，美国政治学会理事
巴巴拉·塔奇曼的历史是自立的，根本用不着任何理论支持。它就是让读者着迷了，它让他们得以如此接近过去的历史，这接近的程度是前所未有的。
——费正清，美国著名历史学者、汉学家
只要具有足够的艺术性，专业历史题材作品也可以达到文学的高度。这部著作极佳地阐释了这一点。
——《纽约时报》
一部精彩的军事史，她笔下的一战首月，其精彩程度正如丘吉尔所说，“戏剧也无法企及”。
——《新闻周刊》
比小说更具戏剧性……高超的叙述，精妙的结构，优雅的文笔，从始至终都保持极佳的节奏。
——《芝加哥论坛报》
【内容简介】
一战终结了历史意义上的19世纪，标志着现代世界的开端。作为历史的转折点，“这个可怕8月的僵局，决定了其后战争的进程和达成和平的条件，并推动后来两次大战间情势的演变，以及第二次世界大战的发生”。但在大战爆发前夕，欧洲绝大多数政客、知识分子与企业主都没有意识到他们与即将爆发的巨大危机只有一尺之隔。
在这部普利策奖经典著作中，巴巴拉·塔奇曼透过生动的历史场景还原、丰富的细节勾勒以及坚实的史料支撑，精彩地展现了1914年8月期间危机的形成、爆发以及大战初期的战役，叩问了是什么让帝王、政客和将领踏进一场无人希望发生，且绝大多数人都认为不可能会发生的世界大战。本书面世后不久即发生了几乎引发核战争的“古巴导弹危机”，时任美国总统肯尼迪正是从本书中汲取了历史教训，使美苏和平化解了危机。这些历史教训对当今世界仍具有深刻的启发意义。
巴巴拉·塔奇曼以高超的叙事手法，带读者走入时人时事，忘记已知结局，使故事悬念感十足。她对人物的刻画尤其传神，且能冷静地跳过道德判断，避免苛责，用极为人性的笔法描述了一个个充满缺陷的人如何将世界引向希腊悲剧般的结局。

Allison Brody is thirty-two and newly arrived on the East Coast after just managing to flee her movie producer boyfriend. She has some money, saved up from years of writing and waitressing, and so she spends it, buying a small house on the beach. But then a Category 3 hurricane makes landfall and scatters her home up and down the shore, leaving Allison adrift.
Should she go home from the bar with the strange cameraman and stay in his guest room? Is that a glass vase he smashed on her skull? Can she wipe the blood from her eyes, get in her car, and drive to her mother's? Does she really love the brain surgeon who saved her, or is she just using him for his swimming pool? And is it possible to ever truly heal without seeking some measure of revenge?
A gripping, provocative novel that walks a knife's edge between comedy and horror,
is the work of a singular talent, a novelist unafraid to explore the intersection of love, sex, violence, and freedom--while celebrating the true joy that can be found in a great swim and a good turkey sandwich.

Federal housing finance policy and mortgage-backed securities have gained widespread attention in recent years because of the 2008 financial crisis, but issues of government credit have been part of American life since the nation's founding. From the 1780s, when a watershed national land credit policy was established, to the postwar foundations of our current housing finance system,
examines the evolution of securitization and federal credit programs. Sarah Quinn shows that since the Westward expansion, the U.S. government has used financial markets to manage America's complex social divides, and politicians and officials across the political spectrum have turned to land sales, home ownership, and credit to provide economic opportunity without the appearance of market intervention or direct wealth redistribution.
Highly technical systems, securitization, and credit programs have been fundamental to how Americans determined what they could and should owe one another. Over time, government officials embraced credit as a political tool that allowed them to navigate an increasingly complex and fractured political system, affirming the government's role as a consequential and creative market participant. Neither intermittent nor marginal, credit programs supported the growth of powerful industries, from railroads and farms to housing and finance; have been used for disaster relief, foreign policy, and military efforts; and were promoters of amortized mortgages, lending abroad, venture capital investment, and mortgage securitization.
Illuminating America's market-heavy social policies,
illustrates how political institutions became involved in the nation's lending practices.

Over the last half-billion years, there have been five mass extinctions, when the diversity of life on earth suddenly and dramatically contracted. Scientists around the world are currently monitoring the sixth extinction, predicted to be the most devastating extinction event since the asteroid impact that wiped out the dinosaurs. This time around, the cataclysm is us.
In prose that is at once frank, entertaining, and deeply informed,
writer Elizabeth Kolbert tells us why and how human beings have altered life on the planet in a way no species has before. Interweaving research in half a dozen disciplines, descriptions of the fascinating species that have already been lost, and the history of extinction as a concept, Kolbert provides a moving and comprehensive account of the disappearances occurring before our very eyes. She shows that the sixth extinction is likely to be mankind's most lasting legacy, compelling us to rethink the fundamental question of what it means to be human.

As we taste, chew, swallow, digest, and excrete, our foods transform us, while our eating, in its turn, affects the wider earthly environment. In Eating in Theory Annemarie Mol takes inspiration from these transformative entanglements to rethink what it is to be human. Drawing on fieldwork at food conferences, research labs, health care facilities, restaurants, and her own kitchen table, Mol reassesses the work of authors such as Hannah Arendt, Maurice Merleau-Ponty, Hans Jonas, and Emmanuel Levinas. They celebrated the allegedly unique capability of humans to rise above their immediate bodily needs. Mol, by contrast, appreciates that as humans we share our fleshy substance with other living beings, whom we cultivate, cut into pieces, transport, prepare, and incorporate—and to whom we leave our excesses. This has far-reaching philosophical consequences. Taking human eating seriously suggests a reappraisal of being as transformative, knowing as entangling, doing as dispersed, and relating as a matter of inescapable dependence.

Insulated from the dust, noise, and crowds churning outside, China's luxury hotels are staging areas for the new economic and political landscape of the country. These hotels, along with other emerging service businesses, offer an important, new source of employment for millions of workers, but also bring to light levels of inequality that surpass most developed nations.
Examining how gender enables the globalization of markets and how emerging forms of service labor are changing women's social status in China,
reveals the forms of social inequality produced by shifts in the economy. No longer working for the common good as defined by the socialist state, service workers are catering to the individual desires of consumers. This economic transition ultimately affords a unique opportunity to investigate the possibilities and current limits for better working conditions for the young women who are enabling the development of capitalism in China.

presents a new framework for the neuroscientific study of emotion across species. Written by Ralph Adolphs and David J. Anderson, two leading authorities on the study of emotion, this accessible and original book recasts the discipline and demonstrates that in order to understand emotion, we need to examine its biological roots in humans and animals. Only through a comparative approach that encompasses work at the molecular, cellular, systems, and cognitive levels will we be able to comprehend what emotions do, how they evolved, how the brain shapes their development, and even how we might engineer them into robots in the future.
Showing that emotions are ubiquitous across species and implemented in specific brain circuits, Adolphs and Anderson offer a broad foundation for thinking about emotions as evolved, functionally defined biological states. The authors discuss the techniques and findings from modern neuroscientific investigations of emotion and conclude with a survey of theories and future research directions.
Featuring color illustrations throughout,
synthesizes the latest in neuroscientific work to provide deeper insights into how emotions function in all of us.

INSTANT NEW YORK TIMES and LOS ANGELES TIMES BESTSELLER
“Brilliant . . . riveting, scary, cogent, and cleverly argued.”—Beth Macy, author of Dopesick,
as heard on Fresh Air

This book is about pleasure. It’s also about pain. Most important, it’s about how to find the delicate balance between the two, and why now more than ever finding balance is essential. We’re living in a time of unprecedented access to high-reward, high-dopamine stimuli: drugs, food, news, gambling, shopping, gaming, texting, sexting, Facebooking, Instagramming, YouTubing, tweeting . . . The increased numbers, variety, and potency is staggering. The smartphone is the modern-day hypodermic needle, delivering digital dopamine 24/7 for a wired generation. As such we’ve all become vulnerable to compulsive overconsumption.
 
In Dopamine Nation, Dr. Anna Lembke, psychiatrist and author, explores the exciting new scientific discoveries that explain why the relentless pursuit of pleasure leads to pain . . . and what to do about it. Condensing complex neuroscience into easy-to-understand metaphors, Lembke illustrates how finding contentment and connectedness means keeping dopamine in check. The lived experiences of her patients are the gripping fabric of her narrative. Their riveting stories of suffering and redemption give us all hope for managing our consumption and transforming our lives. In essence, Dopamine Nation shows that the secret to finding balance is combining the science of desire with the wisdom of recovery.

Karl Deisseroth has spent his life pursuing truths about the human mind, both as a practicing clinical psychiatrist and as a researcher who created the revolutionary field of optogenetics, which allows us to decipher the brain's inner workings using light. In
, he combines his groundbreaking access to the brain's inner circuitry with a deep empathy for his patients to examine what mental illness reveals about the mind and the origin of human feelings--how the broken can illuminate the unbroken.
An internationally acclaimed professor of bioengineering and psychiatry at Stanford, Deisseroth's true passion is clinical psychiatry, and it is the stories of his patients that form the backbone of
. Through these case studies, he tells the larger story of how we can understand the physical and biological origins of human emotion in the brain. As such, he describes vividly how humans experience feelings both in the simple and ancient circuits of our brains and in the poignant moments of suffering in our daily lives. The stories of Deisseroth's patients are rich with humanity and shine an unprecedented light on the self and the ways in which it breaks down. A young woman with an eating disorder reveals how the mind can rebel against the brain's most primitive drives of hunger and thirst; while an older gentleman, smothered into silence by depression and dementia, illuminates how humans evolved to feel joy and its absence; and a lonely Uyghur woman far from home teaches the importance of rich social bonds.
An illuminating and essential work,
transforms the way we understand the brain as a biological and as an emotional object.
A groundbreaking tour of the human mind that illuminates the biological nature of our inner worlds and emotions, through gripping, moving—and, at times, harrowing—clinical stories
“[A] scintillating and moving analysis of the human brain and emotions.”—Nature
“Beautifully connects the inner feelings within all human beings to deep insights from modern psychiatry and neuroscience.”—Robert Lefkowitz, Nobel Laureate